The Effect Tickets

The Effect Tickets

The Effect: What to expect - 1
The Effect Tickets

About The Effect

Who I am
Is not
A side effect.

Hearts and minds racing, Connie and Tristan are falling for each other fast. But is their sudden and intoxicating chemistry real, or a side effect of a new antidepressant?

As two young volunteers in a clinical drug trial, their illicit romance poses startling dilemmas for the supervising doctors.

Jamie Lloyd (Cyrano de Bergerac) directs Lucy Prebble’s (Succession) funny and intimate examination of love and ethics.

Paapa Essiedu (I May Destroy You) plays Tristan and Taylor Russell (Bones and All) plays Connie.

Run time

1h 40m (incl. interval)

Start date

1st August, 2023

End date

7th October, 2023



This production contains strong language and adult themes.

49 Reviews



557 Reviews | 136 Followers
Intelligent, Great staging, Must see

See it if you like well-written, gripping theater that's both intellectually and emotionally stimulating, with exceptional cast and outstanding design

Don’t see it if you don't like slick lighting effects & loud music, it might feel a little alienating and distancing at times, but I felt it added urgency.

Catherine 352

Catherine 352

109 Reviews | 12 Followers
Thought-provoking, Resonant, Profound, Great writing, Great acting

See it if you’d like a play that makes you feel and think. If you are interested in mind and science. If you like a cleverly written text played well.

Don’t see it if you have difficulties with depression related with relationships. If you prefer physically or visually entertaining theatres than wordy ones



151 Reviews | 20 Followers
Great acting, Dizzying, Absorbing

See it if You want to see some excellent actors doing excellent acing

Don’t see it if You get irritated by writing and are waiting for a set

Red Bus Londinium

Red Bus Londinium

139 Reviews | 11 Followers
Relevant, Thought-provoking, Great staging, Clever, Absorbing

See it if you want to see a well-acted, well-staged and riveting play that cleverly explores what is and is not real when chemicals are involved.

Don’t see it if you want an accurate picture of medical trial protocol. I went with someone in the industry and they could point out many inconsistencies.

Important information

There are strobe/flashing lights, smoke and haze effects, with loud music. Some scenes include sexual content, physical aggression, depictions of seizures and references to depression, anxiety and suicide.


Lyttelton Theatre

National Theatre, South Bank, London, United Kingdom, SE1 9PX


Location: West End
Railway station: Waterloo
Bus numbers: (Waterloo Road) 1, 4, 26, 59, 68, 76, 139, 168, 171, 172, 176, 188, 243, 341, 521, RV1, X68
Night bus numbers: (Waterloo Road) 139, 176, 188, 243, 341, N1, N68, N76, N171, N343
Car park: National Theatre, Upper Ground (1min)
Directions from tube: (10mins) Follow signs for exits to the South Bank. This should lead you to an underground pedestrian passage called ‘Sutton Walk’ that emerges at the South Bank. Turn right and walk along the river Thames until you see the National Theatre.


Unfortunately, tickets for this event are no longer available.

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